DNA biophysics

Velocity of DNA during translocation through a solid state nanopore

While understanding translocation of DNA through a solid-state nanopore is vital for exploiting its potential for sensing and sequencing at the single-molecule level, surprisingly little is known about the dynamics of the propagation of DNA through …

Non-equilibrium folding of individual DNA molecules recaptured up to 1000 times in a solid state nanopore

We investigate translocation of linear and circular double-stranded DNA molecules through solid state nanopores where each molecule is recaptured and re-translocated many times. Single molecules can be recaptured by switching voltage polarity for …